Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.62 |
| ▸ | LOX | P28300 | 3/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CFD | P00746 | 2/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | F11 | P03951 | 1/20 | 0.55 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.55 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19953267 | 0.98 | LOXL2 (0.62) | LOXL2LOXHDAC1HDAC2HDAC8 | |
| SCHEMBL6681834 | 0.90 | KCNK3 (0.69) | KCNK3KCNK9KMT2ACFDSIRT1 | |
| SCHEMBL15653197 | 0.88 | PTGS1 (0.59) | LOXL2LOXKMT2AROCK2LMNA | |
| SCHEMBL15650701 | 0.86 | PTGS1 (0.60) | LOXL2LOXKCNK3KCNK9KMT2A | |
| SCHEMBL1552986 | 0.86 | NT5E (0.62) | LOXL2LOXKCNK3KMT2AROCK2 | |
| SCHEMBL27680245 | 0.86 | ROCK2 (0.55) | LOXL2LOXHDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL5458845 | 0.85 | NT5E (0.61) | LOXL2LOXKCNK3KMT2AROCK2 | |
| SCHEMBL6677659 | 0.85 | PTPN1 (0.65) | LOXL2LOXHDAC1HDAC2HDAC8 | |
| SCHEMBL1857575 | 0.85 | PTPN1 (0.65) | KCNK3KCNK9KMT2ASIRT1NPC1 | |
| SCHEMBL12228481 | 0.84 | HDAC1 (0.61) | HDAC1HDAC2HDAC8HDAC6KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |