Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27660642 | 0.98 | CES2 (0.38) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL27660646 | 0.80 | HIF1A (0.36) | ALDH1A1LMNASMN1; SMN2ESR1HIF1A | |
| Hydrochloric Acid SCHEMBL27660645 | 0.79 | ESR1 (0.35) | ALDH1A1SMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL2482717 | 0.79 | CUL4A (0.45) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL28748414 | 0.79 | CES2 (0.43) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL2482336 | 0.76 | CES2 (0.45) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL6223306 | 0.76 | CUL4A (0.41) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL29137860 | 0.73 | GSK3B (0.41) | LMNAGSK3BSMN1; SMN2ESR1HIF1A | |
| SCHEMBL15911023 | 0.71 | RAB9A (0.38) | CES2CES1ALDH1A1LMNAGSK3B | |
| SCHEMBL29131729 | 0.71 | KMT2A (0.48) | ALDH1A1LMNASMN1; SMN2ESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1956971-A | Novel fused heterocycles and application thereof | ASTRAZENECA AB (SE) | 2007-05-02 | — | — | CN | disclosed |