Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27660645 | 0.98 | ESR1 (0.35) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL27680681 | 0.80 | CES2 (0.39) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL27654025 | 0.79 | LMNA (0.32) | KMT2ASMN1; SMN2ACHEKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27660642 | 0.79 | CES2 (0.38) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL6245943 | 0.69 | SMN1; SMN2 (0.37) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL525049 | 0.67 | MMP1 (0.45) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL4246892 | 0.66 | KMT2A (0.63) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27610314 | 0.66 | MMP1 (0.44) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL15547239 | 0.66 | ALOX15 (0.58) | HIF1AESR1KMT2ARECQLSMN1; SMN2 | |
| SCHEMBL29137860 | 0.64 | GSK3B (0.41) | HIF1AESR1KMT2ARECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1956971-A | Novel fused heterocycles and application thereof | ASTRAZENECA AB (SE) | 2007-05-02 | — | — | CN | disclosed |