Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.37 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680730 | 0.89 | KDM1A (0.44) | KDM1AOPRM1ESR2ESR1SIGMAR1 | |
| SCHEMBL27660719 | 0.88 | OPRM1 (0.38) | KDM1AOPRM1ESR2ESR1SLC6A2 | |
| SCHEMBL27660873 | 0.88 | OPRM1 (0.38) | KDM1AOPRM1ESR2ESR1SLC6A2 | |
| SCHEMBL27660688 | 0.81 | KDM1A (0.47) | KDM1ASIGMAR1 | |
| SCHEMBL2498788 | 0.71 | ESR2 (0.51) | KDM1AESR2ESR1SIGMAR1SRD5A1 | |
| SCHEMBL8017548 | 0.69 | OPRM1 (0.38) | OPRM1 | |
| SCHEMBL21344584 | 0.69 | KDM1A (0.47) | KDM1AESR2ESR1SIGMAR1SLC6A4 | |
| SCHEMBL7980930 | 0.68 | KDM1A (0.37) | KDM1AESR2ESR1SRD5A1SRD5A2 | |
| SCHEMBL13799465 | 0.67 | SRD5A1 (0.49) | KDM1ASIGMAR1SRD5A1HTR2AHTR2C | |
| SCHEMBL8556494 | 0.67 | KDM1A (0.41) | KDM1AOPRM1ESR2ESR1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950328-A | Phenyl indan derivatives | LUNDBECK & CO AS H (DK) | 2007-04-18 | — | — | CN | disclosed |