Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22190366 | 0.85 | CES2 (0.49) | CES2CES1GRM8GRM4CNR2 | |
| SCHEMBL11076601 | 0.82 | CES2 (0.42) | CES2CES1GRM8GRM4CNR2 | |
| SCHEMBL11080075 | 0.74 | CES2 (0.47) | CES2CES1GRM8GRM4CNR2 | |
| SCHEMBL28200284 | 0.73 | CES2 (0.50) | CES2CES1GRM8GRM4CNR2 | |
| SCHEMBL9187166 | 0.73 | PDE2A (0.44) | CES2CES1ACP3FFAR1 | |
| SCHEMBL23080122 | 0.72 | CES2 (0.50) | CES2CES1GRM8GRM4CNR2 | |
| SCHEMBL2316007 | 0.72 | TAAR1 (0.57) | CES2CES1FFAR1MAOB | |
| SCHEMBL1226196 | 0.71 | CES2 (0.45) | CES2CES1FFAR1 | |
| SCHEMBL1226200 | 0.71 | CES2 (0.45) | CES2CES1FFAR1 | |
| SCHEMBL2692867 | 0.71 | CES2 (0.45) | CES2CES1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950085-A | 3- (4-heteroarylcyclohexylamino) cyclopentanecarboxamides as chemokine receptor modulators | INCYTE CORP (US) | 2007-04-18 | — | — | CN | disclosed |