Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680914 | 0.85 | CES2 (0.44) | CES2CES1HSD11B1GRM8GRM4 | |
| SCHEMBL23080122 | 0.84 | CES2 (0.50) | CES2CES1HSD11B1GRM8GRM4 | |
| SCHEMBL11076601 | 0.83 | CES2 (0.42) | CES2CES1GRM8GRM4KIF11 | |
| SCHEMBL28957128 | 0.82 | AOC3 (0.47) | — | |
| SCHEMBL28957129 | 0.82 | AOC3 (0.47) | — | |
| SCHEMBL2743313 | 0.81 | HSD11B1 (0.50) | CES2CES1HSD11B1GRM8GRM4 | |
| SCHEMBL29570765 | 0.80 | SLC6A2 (0.47) | CES2CES1HSD11B1GRM8GRM4 | |
| SCHEMBL29262298 | 0.80 | HSD11B1 (0.49) | CES2CES1HSD11B1GRM8GRM4 | |
| SCHEMBL22190392 | 0.79 | BCAT2 (0.36) | GSK3B | |
| SCHEMBL4052142 | 0.79 | ALOX5 (0.47) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |