Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.41 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461785 | 0.82 | XDH (0.56) | XDHKDM4EKDM5AKDM3AJMJD1C | |
| SCHEMBL2162964 | 0.79 | CYP1A2 (0.57) | KDM4ECYP1A2MAPTALDH1A1KMT2A | |
| SCHEMBL27700143 | 0.79 | XDH (0.50) | XDHKDM4EKDM5AKDM3AJMJD1C | |
| SCHEMBL8365585 | 0.78 | HPGDS (0.46) | CYP1A2ALDH1A1KMT2AHPGDSMEN1 | |
| SCHEMBL29859342 | 0.78 | KMO (0.57) | KDM4EKDM5AKDM3ASLC22A12MAPT | |
| SCHEMBL1505808 | 0.77 | KDM4E (0.57) | XDHKDM4EKDM5AKDM3AJMJD1C | |
| SCHEMBL696116 | 0.76 | XDH (0.50) | XDHKDM4EKDM5AKDM3AJMJD1C | |
| SCHEMBL28988552 | 0.76 | XDH (0.56) | XDHKDM4EKDM5AKDM3AJMJD1C | |
| SCHEMBL31301691 | 0.76 | MAP4K4 (0.56) | XDHKDM4EKDM5AKDM3AJMJD1C | |
| Hydrochloric Acid SCHEMBL7968706 | 0.75 | XDH (0.49) | XDHKDM4EKDM5AKDM3AJMJD1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101023063-A | Azine-carboxamides as anti-cancer agents | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | CN | disclosed |