Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 13/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034897 | 0.83 | SPR (0.44) | KMT2AKDM4ENFE2L2KEAP1ALDH1A1 | |
| SCHEMBL4033790 | 0.80 | PDE4B (0.48) | KMT2AKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3678140 | 0.78 | NFE2L2 (0.58) | KMT2AKDM4ENFE2L2KEAP1ALDH1A1 | |
| SCHEMBL20378225 | 0.74 | KEAP1 (0.54) | KMT2ANFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL826414 | 0.74 | NFE2L2 (0.54) | KMT2ANFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL574416 | 0.74 | KDM4E (0.49) | KMT2AKDM4EALDH1A1SMN1; SMN2SPR | |
| SCHEMBL24813930 | 0.73 | NFE2L2 (0.52) | KMT2AKDM4ENFE2L2KEAP1ALDH1A1 | |
| SCHEMBL1694496 | 0.73 | KDM4E (0.48) | KMT2AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25251448 | 0.73 | KDM4E (0.48) | KMT2AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4032991 | 0.72 | KDM4E (0.38) | KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930144-A | 3-'4-heterocyclyl -1,2,3,-triazol-1-yl!-n-aryl-benzamides as inhibitors of the cytokines production for the treatment of chronic inflammatory diseases | BOEHRINGER INGELHEIM PHARMA (US) | 2007-03-14 | — | — | CN | disclosed |