Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.78 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.78 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.78 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.78 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734120 | 0.88 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18064956 | 0.88 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27681896 | 0.87 | HDAC3 (0.58) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27701331 | 0.85 | MCL1 (0.57) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27701329 | 0.79 | SMN1; SMN2 (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2408087 | 0.75 | HDAC1 (0.70) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1937951 | 0.74 | HDAC1 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30763162 | 0.73 | HDAC3 (0.74) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL21595522 | 0.73 | HDAC3 (0.74) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30416073 | 0.72 | HDAC1 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087601-A | Compounds for inhibiting copper-containing amine oxidases and uses thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-12-12 | — | — | CN | disclosed |