Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27681897 | 0.87 | HDAC3 (0.78) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27701331 | 0.78 | MCL1 (0.57) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27701329 | 0.76 | SMN1; SMN2 (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL31734120 | 0.74 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18064956 | 0.74 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL28499435 | 0.70 | SMN1; SMN2 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL27701359 | 0.69 | RAB9A (0.63) | SMN1; SMN2KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL27681863 | 0.69 | KDM4E (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18257157 | 0.69 | SMN1; SMN2 (0.69) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL5919246 | 0.67 | MAPT (0.62) | HDAC3HDAC1HDAC2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087601-A | Compounds for inhibiting copper-containing amine oxidases and uses thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-12-12 | — | — | CN | disclosed |