Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27681897 | 0.85 | HDAC3 (0.78) | MCL1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27701329 | 0.85 | SMN1; SMN2 (0.55) | MCL1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27681896 | 0.78 | HDAC3 (0.58) | MCL1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14517926 | 0.77 | PRKD3 (0.75) | SMN1; SMN2MAPTKDM4EHTTCHEK1 | |
| SCHEMBL27681863 | 0.77 | KDM4E (0.43) | MCL1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28768801 | 0.73 | MEN1 (0.56) | SMN1; SMN2MAPTKDM4EMEN1NPC1 | |
| SCHEMBL18064949 | 0.73 | MCL1 (0.73) | MCL1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28613060 | 0.72 | MCL1 (0.68) | MCL1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29643990 | 0.72 | MCL1 (0.68) | MCL1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27701359 | 0.72 | RAB9A (0.63) | ALDH1A1TSHRSMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087601-A | Compounds for inhibiting copper-containing amine oxidases and uses thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-12-12 | — | — | CN | disclosed |