Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 6/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.36 |
| ▸ | PDE5A | O76074 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778930 | 0.91 | KDM4E (0.43) | KDM4EMAPTMAPK1CASP1CASP7 | |
| SCHEMBL4776084 | 0.86 | TBXAS1 (0.42) | TBXAS1KDM4EMAPTMAPK1CASP1 | |
| SCHEMBL27682184 | 0.86 | KDM4E (0.36) | KDM4EMAPTMAPK1CASP1CASP7 | |
| SCHEMBL27682201 | 0.85 | KDM4E (0.36) | TBXAS1KDM4EMAPTMAPK1CASP1 | |
| SCHEMBL5367661 | 0.85 | KDM4E (0.38) | KDM4EMAPTMAPK1CASP1CASP7 | |
| SCHEMBL4770239 | 0.84 | KDM4E (0.39) | KDM4EMAPTMAPK1CASP1CASP7 | |
| SCHEMBL27682168 | 0.83 | TBXAS1 (0.42) | TBXAS1KDM4EMAPTMAPK1CASP1 | |
| SCHEMBL4777489 | 0.82 | TBXAS1 (0.44) | TBXAS1KDM4EMAPTMAPK1CASP1 | |
| SCHEMBL4775027 | 0.82 | MEN1 (0.48) | TBXAS1KDM4EL3MBTL1GAAMEN1 | |
| SCHEMBL27682165 | 0.82 | ADORA2A (0.41) | KDM4EMAPTMAPK1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |