Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27662603 | 0.99 | SIGMAR1 (0.37) | MAT2ASIGMAR1PDE10AACVR2ATGFBR2 | |
| SCHEMBL27682186 | 0.98 | MAT2A (0.36) | MAT2ASIGMAR1PDE10AACVR2ATGFBR2 | |
| SCHEMBL27662702 | 0.96 | MAT2A (0.39) | MAT2ASIGMAR1PDE10APSEN1PSEN2 | |
| SCHEMBL27662623 | 0.89 | MAT2A (0.35) | MAT2APDE10AACVR2ATGFBR2PDE4B | |
| SCHEMBL27662634 | 0.85 | MAT2A (0.38) | MAT2APDE10APSEN1PSEN2APH1B | |
| SCHEMBL27682215 | 0.85 | MAT2A (0.38) | MAT2APDE10APSEN1PSEN2APH1B | |
| SCHEMBL27682256 | 0.84 | SIGMAR1 (0.36) | MAT2ASIGMAR1PSEN1PSEN2APH1B | |
| SCHEMBL4778900 | 0.83 | SIGMAR1 (0.35) | MAT2ASIGMAR1PSEN1PSEN2APH1B | |
| SCHEMBL27662605 | 0.83 | SIGMAR1 (0.37) | MAT2ASIGMAR1PSEN1PSEN2APH1B | |
| SCHEMBL27662579 | 0.83 | PDE10A (0.39) | MAT2ASIGMAR1PDE10APSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |