Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 8/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27662605 | 0.99 | SIGMAR1 (0.37) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27682188 | 0.98 | SIGMAR1 (0.36) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27662703 | 0.96 | PRKAA2 (0.36) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27662625 | 0.89 | PDE5A (0.33) | PRKAA2PDE5APDE4BMAT2APIK3CA | |
| SCHEMBL4775049 | 0.88 | PTGS2 (0.37) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4770021 | 0.86 | PTGS2 (0.37) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27682217 | 0.85 | PRKAA2 (0.36) | PRKAA2PDE5AMAT2APIK3CAMTOR | |
| SCHEMBL27662635 | 0.85 | PRKAA2 (0.36) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27682255 | 0.84 | MAT2A (0.36) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4779562 | 0.83 | MAT2A (0.36) | SIGMAR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980927-A | Pyrazolopyridine derivatives | ASTELLAS PHARMA INC (JP) | 2007-06-13 | — | — | CN | disclosed |