Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074609 | 0.83 | SLC6A2 (0.56) | SLC6A2SLC6A4CYP1A2KMT2ACYP2D6 | |
| SCHEMBL27682972 | 0.80 | HTR6 (0.39) | SLC6A2SLC6A4OPRK1PLA2G4AHTR6 | |
| SCHEMBL27663370 | 0.68 | SLC6A4 (0.43) | SLC6A2SLC6A4CYP1A2KMT2ACYP2D6 | |
| SCHEMBL27719828 | 0.68 | ALOX5 (0.49) | SLC6A2SLC6A4KMT2A | |
| SCHEMBL2074378 | 0.67 | SLC6A2 (0.63) | SLC6A2SLC6A4OPRK1CYP1A2OPRM1 | |
| SCHEMBL27683071 | 0.65 | SLC6A4 (0.55) | SLC6A2SLC6A4HTR2C | |
| SCHEMBL27682985 | 0.64 | SLC6A4 (0.45) | SLC6A2SLC6A4OPRK1OPRM1HTR2C | |
| SCHEMBL28135466 | 0.64 | HTR6 (0.42) | SLC6A2SLC6A4OPRK1PLA2G4AHTR6 | |
| SCHEMBL28599022 | 0.64 | CA4 (0.41) | CYP1A1CYP1A2CYP1B1ALDH1A1KMT2A | |
| SCHEMBL23927940 | 0.62 | HTR2C (0.44) | ALDH1A1HTR2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993321-A | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | CN | disclosed |