Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599095 | 0.86 | DGKA (0.54) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL3093520 | 0.86 | DGKA (0.54) | DGKADNM1ADRA2AADRA1AFOLH1 | |
| SCHEMBL11599018 | 0.86 | DGKA (0.48) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL28962579 | 0.84 | DGKA (0.43) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL3515972 | 0.84 | DGKA (0.46) | DGKADNM1ADRA2AADRA1AFOLH1 | |
| SCHEMBL11598259 | 0.84 | DGKA (0.58) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL30517203 | 0.84 | DGKA (0.46) | DGKADNM1ADRA2AADRA1AFOLH1 | |
| SCHEMBL11601599 | 0.84 | DGKA (0.58) | DGKADNM1ADRA2AADRA1AMAPT | |
| SCHEMBL3517280 | 0.84 | DGKA (0.46) | DGKADNM1ADRA2AADRA1AFOLH1 | |
| SCHEMBL3515561 | 0.82 | DGKA (0.45) | DGKADNM1ADRA2AADRA1AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101033238-B | Preparation method and use for purine compounds double amino acid ester | SHANGHAI INST MATERIA MEDICA | 2011-02-16 | — | — | CN | disclosed |
| CN-101033238-A | Preparation method and use for purine compounds double amino acid ester | SHANGHAI INST MATERIA MEDICA (CN) | 2007-09-12 | — | — | CN | disclosed |