Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517927 | 0.98 | DGKA (0.48) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL30517203 | 0.98 | DGKA (0.46) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL11677087 | 0.95 | DGKA (0.50) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL3517120 | 0.95 | DGKA (0.50) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL5342062 | 0.93 | DGKA (0.54) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL14336959 | 0.93 | DGKA (0.54) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL3521469 | 0.93 | DGKA (0.54) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL11356292 | 0.93 | DGKA (0.54) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL3517280 | 0.93 | DGKA (0.46) | DGKAFOLH1DNM1NAAAHTR2C | |
| SCHEMBL10887322 | 0.93 | HTR2C (0.46) | DGKAFOLH1DNM1NAAAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | L'OREAL S.A. (FR) | 2005-09-22 | — | — | US | claimed |
| US-20100190902-A1 | ALKYLTIN SULFANYL ESTER THIOLS | CHEMTURA CORPORATION (US) | 2010-07-29 | — | — | US | disclosed |
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | L'OREAL S.A. (FR) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190902-A1 | ALKYLTIN SULFANYL ESTER THIOLS | SULT1E1, SULT1A1, TST | DGKA 4070/4885FOLH1 4882/4885DNM1 3213/4885 |
| US-20050208007-A1 | Composition to permanently reshape the hair containing at least one carboxydithiol | CTH, BHMT2, CRAT | DGKA 3121/4885FOLH1 68/4885DNM1 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.