Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768140 | 1.00 | SGMS2 (0.37) | SGMS2L3MBTL1EDNRAABCG2HDAC3 | |
| SCHEMBL2768136 | 0.78 | SGMS2 (0.42) | SGMS2SGMS1 | |
| SCHEMBL2785783 | 0.72 | SGMS2 (0.41) | SGMS2EDNRASGMS1 | |
| SCHEMBL2784102 | 0.72 | SGMS2 (0.41) | SGMS2EDNRASGMS1 | |
| SCHEMBL3562330 | 0.71 | SGMS2 (0.37) | SGMS2EDNRASGMS1 | |
| SCHEMBL2771311 | 0.71 | SGMS2 (0.43) | SGMS2EDNRAHDAC3HDAC4HDAC1 | |
| SCHEMBL2787950 | 0.70 | SGMS2 (0.42) | SGMS2EDNRAALDH1A1SGMS1 | |
| SCHEMBL2787342 | 0.69 | SGMS2 (0.41) | SGMS2EDNRAALDH1A1SGMS1 | |
| SCHEMBL2440114 | 0.68 | SENP7 (0.44) | SGMS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12330750 | 0.68 | SGMS2 (0.54) | SGMS2EDNRASGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |