Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 7/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2440688 | 0.72 | KDR (0.46) | SGMS2EDNRASGMS1MAOAMAOB | |
| SCHEMBL2768136 | 0.71 | SGMS2 (0.42) | SGMS2SGMS1CYP1A2CYP2D6 | |
| SCHEMBL2768342 | 0.71 | SGMS2 (0.37) | SGMS2EDNRASGMS1 | |
| SCHEMBL2768140 | 0.71 | SGMS2 (0.37) | SGMS2EDNRASGMS1 | |
| SCHEMBL12330750 | 0.70 | SGMS2 (0.54) | SGMS2EDNRASGMS1 | |
| SCHEMBL2785783 | 0.69 | SGMS2 (0.41) | SGMS2EDNRASGMS1 | |
| SCHEMBL2784102 | 0.69 | SGMS2 (0.41) | SGMS2EDNRASGMS1 | |
| SCHEMBL2440114 | 0.67 | SENP7 (0.44) | SGMS2SGMS1 | |
| SCHEMBL5126449 | 0.61 | NPC1 (0.48) | SGMS2EDNRAMAOB | |
| SCHEMBL15119818 | 0.61 | MAPT (0.44) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696238-B2 | Substituted benzo[d]isoxazol-3-yl amine compounds as analgesics | GRUENENTHAL GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | GRUENENTHAL GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176915-A1 | Substituted Benzo[d]isoxazol-3-yl Amine Compounds as Analgesics | KCNQ1, KCNQ2, KCNQ3 | SGMS2 4737/4885FAAH 1283/4885MGLL 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.