Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27684202 | 0.82 | PKM (0.57) | MEN1KMT2ALMNANR1H4NPC1 | |
| Benzene SCHEMBL28089344 | 0.78 | KMT2A (0.64) | MEN1KMT2ALMNANR1H4NPC1 | |
| (Chloromethyl)Benzene SCHEMBL27444948 | 0.78 | KMT2A (0.50) | MEN1KMT2ALMNANPC1RAB9A | |
| Phenylacetic Acid SCHEMBL27601689 | 0.78 | KMT2A (0.50) | KMT2ALMNANR1H4NPC1RAB9A | |
| Phenol SCHEMBL27593878 | 0.77 | KMT2A (0.55) | MEN1KMT2ALMNANR1H4NPC1 | |
| SCHEMBL27348049 | 0.77 | SMN1; SMN2 (0.52) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10599853 | 0.76 | MEN1 (0.79) | MEN1KMT2ALMNANR1H4NPC1 | |
| SCHEMBL27290130 | 0.76 | KMT2A (0.68) | MEN1KMT2ALMNANR1H4NPC1 | |
| SCHEMBL3675252 | 0.76 | RAB9A (0.65) | MEN1KMT2ALMNANR1H4NPC1 | |
| Toluene SCHEMBL28309354 | 0.75 | KMT2A (0.55) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101084178-B | (biphenyl) carboxylic acids and derivatives thereof | CELLZOME AG | 2012-03-28 | — | — | CN | disclosed |
| CN-101084178-A | (Biphenyl) carboxylic acids and derivatives thereof | CELLZOME AG (DE) | 2007-12-05 | — | — | CN | disclosed |