Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | KDM4A | O75164 | 1/20 | 0.62 |
| ▸ | ANPEP | P15144 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658527 | 0.92 | POLB (0.63) | POLBKDM4AANPEPCTSSCTSK | |
| SCHEMBL27658471 | 0.83 | KDM4A (0.60) | POLBKDM4ACTSSCTSKMMP8 | |
| SCHEMBL12381969 | 0.82 | CTSK (0.56) | POLBKDM4ACTSSCTSKMMP8 | |
| SCHEMBL13182988 | 0.81 | POLB (0.68) | POLBKDM4AKMT2ACYP2D6CYP2C9 | |
| SCHEMBL13073874 | 0.81 | ANPEP (0.63) | POLBANPEPMMP8KMT2ACYP2D6 | |
| SCHEMBL8613610 | 0.81 | ANPEP (0.63) | POLBANPEPMMP8KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL8617103 | 0.79 | ANPEP (0.61) | POLBANPEPMMP8KMT2ACYP2D6 | |
| SCHEMBL4138386 | 0.79 | MMP8 (0.65) | POLBANPEPMMP8KMT2ACYP2D6 | |
| SCHEMBL7866857 | 0.79 | KMT2A (0.81) | POLBANPEPKMT2ACYP2D6CYP2C9 | |
| SCHEMBL13569363 | 0.78 | CNR1 (0.81) | POLBCNR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910144-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | claimed |
| CN-1910144-B | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD | 2010-06-09 | — | — | CN | disclosed |
| CN-1910144-A | Sulfonamide derivatives for the treatment of diseases | PFIZER LTD (US) | 2007-02-07 | — | — | CN | disclosed |