Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 5/20 | 0.39 |
| ▸ | FPR3 | P25089 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706525 | 0.87 | RAB9A (0.50) | RAB9AMAPTNPC1KDM1AHDAC1 | |
| SCHEMBL13547516 | 0.82 | MAPT (0.53) | RAB9AMAPTNPC1KDM1AHDAC1 | |
| SCHEMBL9926020 | 0.81 | MAPT (0.51) | RAB9AMAPTNPC1KDM1AHDAC1 | |
| SCHEMBL2642294 | 0.81 | MAPT (0.51) | RAB9AMAPTNPC1KDM1AHDAC1 | |
| SCHEMBL14076073 | 0.78 | FPR2 (0.51) | RAB9AMAPTNPC1KDM1AHDAC1 | |
| SCHEMBL9298064 | 0.77 | FPR2 (0.50) | RAB9AMAPTNPC1KDM1AFPR2 | |
| SCHEMBL21333144 | 0.74 | HDAC1 (0.68) | RAB9AMAPTNPC1HDAC1HDAC8 | |
| SCHEMBL21516426 | 0.73 | MAPT (0.42) | RAB9AMAPTNPC1KDM1AFPR2 | |
| SCHEMBL4300645 | 0.72 | HTR2B (0.40) | RAB9AMAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL8280912 | 0.72 | HRH3 (0.63) | RAB9AMAPTNPC1FPR2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006085-A | Substituted hydantoins | HOFFMANN LA ROCHE (CH) | 2007-07-25 | — | — | CN | disclosed |