Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560176 | 0.90 | F2 (0.70) | LMNAF2RAB9APKMKMT2A | |
| SCHEMBL5244678 | 0.86 | F2 (0.70) | LMNAF2RAB9APKMKMT2A | |
| SCHEMBL2464842 | 0.85 | KMT2A (0.65) | LMNAF2RAB9APKMNPC1 | |
| SCHEMBL2615036 | 0.84 | LMNA (0.74) | LMNAF2RAB9APKMNPC1 | |
| SCHEMBL2615037 | 0.84 | LMNA (0.74) | LMNAF2RAB9APKMNPC1 | |
| SCHEMBL10560170 | 0.83 | LMNA (0.59) | LMNAF2RAB9APKMKMT2A | |
| SCHEMBL28051725 | 0.83 | F2 (0.59) | LMNAF2PKMKMT2AMAPT | |
| SCHEMBL22468182 | 0.81 | F2 (0.57) | LMNAF2RAB9APKMKMT2A | |
| SCHEMBL20599493 | 0.81 | LMNA (0.57) | LMNAF2RAB9APKMNPC1 | |
| SCHEMBL94313 | 0.81 | F2 (0.57) | LMNAF2RAB9APKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1930155-B | Acylaminothiazole derivatives, their preparation and their use in therapy | SANOFI AVENTIS | 2011-06-08 | — | — | CN | disclosed |
| CN-1930155-A | Acylaminothiazole derivatives, their preparation and their use in therapy | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | CN | disclosed |