Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560176 | 0.90 | F2 (0.70) | F2LMNACES2CES1KMT2A | |
| SCHEMBL5244678 | 0.86 | F2 (0.70) | F2LMNACES2CES1KMT2A | |
| SCHEMBL4425652 | 0.85 | PARP10 (0.65) | CES2CES1KMT2ATDP1MAPT | |
| Benzoyl Peroxide SCHEMBL10536706 | 0.84 | LMNA (0.74) | F2LMNACES2CES1KMT2A | |
| SCHEMBL10560170 | 0.83 | LMNA (0.59) | F2LMNACES2KMT2ATDP1 | |
| SCHEMBL28051725 | 0.83 | F2 (0.59) | F2LMNACES2CES1KMT2A | |
| SCHEMBL27797228 | 0.82 | F2 (0.53) | F2LMNAKMT2ATDP1MAPT | |
| Benzoyl Peroxide SCHEMBL28015923 | 0.82 | F2 (0.77) | F2LMNACES2CES1KMT2A | |
| SCHEMBL94313 | 0.81 | F2 (0.57) | F2LMNACES2CES1KMT2A | |
| SCHEMBL20599493 | 0.81 | LMNA (0.57) | F2LMNAKMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169596-A1 | DERIVATIVES OF 10-METHYLENE LIPIDS, PROCESS FOR PREPARING SUCH DERIVATIVES AND USE THEREOF | GINKGO BIOWORKS, INC. | 2022-06-02 | — | — | US | disclosed |
| EP-3947339-A1 | DERIVATIVES OF 10-METHYLENE LIPIDS, PROCESS FOR PREPARING SUCH DERIVATIVES AND USE THEREOF | Ginkgo Bioworks, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113906007-A | 10-methylene lipid derivatives, preparation method and application thereof | 银杏生物制品公司 | 2022-01-07 | — | — | CN | disclosed |
| WO-2020193681-A1 | DERIVATIVES OF 10-METHYLENE LIPIDS, PROCESS FOR PREPARING SUCH DERIVATIVES AND USE THEREOF | NOVOGY, INC. (US) | 2020-10-01 | — | — | WO | disclosed |