SCHEMBL27685166

SCHEMBL27685166

O=C(O)N(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ADRA2C P18825 1/20 0.46
KMT2A Q03164 3/20 0.45
NPSR1 Q6W5P4 1/20 0.44
KDM4E B2RXH2 2/20 0.44
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
LMNA P02545 1/20 0.42
HPGD P15428 2/20 0.42
MEN1 O00255 1/20 0.42
HSD11B1 P28845 1/20 0.41
NR3C2 P08235 1/20 0.41
MLYCD O95822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11686024 0.98 L3MBTL1 (0.48) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C
SCHEMBL10937900 0.91 L3MBTL1 (0.53) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C
SCHEMBL27987579 0.89 ATM (0.45) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C
SCHEMBL23070577 0.85 KMT2A (0.49) L3MBTL1TDP1RAB9ASMN1; SMN2KMT2A
SCHEMBL3780927 0.84 SMN1; SMN2 (0.48) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C
SCHEMBL891832 0.83 NPSR1 (0.55) L3MBTL1TDP1RAB9ASMN1; SMN2KMT2A
Benzoylphenylurea SCHEMBL83109 0.83 L3MBTL1 (0.48) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C
SCHEMBL27258081 0.83 RAB9A (0.47) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C
SCHEMBL11686012 0.83 RAB9A (0.47) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C
Benzoylphenylurea SCHEMBL31707309 0.81 TDP1 (0.46) L3MBTL1TDP1RAB9ASMN1; SMN2ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103044863-A Plastic composition, preparation method thereof and plastic product thereform CHINA PETROLEUM & CHEMICAL 2013-04-17 CN claimed
CN-100494272-C Polyester composite material and method for preparing same SHANGHAI GENIUS ADVANCED MAT (CN) 2009-06-03 CN claimed
CN-1990545-A Polyester composite material and method for preparing same SHANGHAI GENIUS ADVANCED MAT (CN) 2007-07-04 CN claimed
CN-103044863-A Plastic composition, preparation method thereof and plastic product thereform CHINA PETROLEUM & CHEMICAL 2013-04-17 CN disclosed
CN-100494272-C Polyester composite material and method for preparing same SHANGHAI GENIUS ADVANCED MAT (CN) 2009-06-03 CN disclosed
CN-1990545-A Polyester composite material and method for preparing same SHANGHAI GENIUS ADVANCED MAT (CN) 2007-07-04 CN disclosed