Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937900 | 0.93 | L3MBTL1 (0.53) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C | |
| SCHEMBL27685166 | 0.84 | L3MBTL1 (0.50) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C | |
| SCHEMBL3783931 | 0.84 | KMO (0.40) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C | |
| Hydrochloric Acid SCHEMBL11686024 | 0.83 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C | |
| SCHEMBL31186281 | 0.82 | CES2 (0.59) | SMN1; SMN2L3MBTL1RAB9ATDP1CES2 | |
| SCHEMBL28075002 | 0.82 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C | |
| SCHEMBL11686012 | 0.81 | RAB9A (0.47) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C | |
| SCHEMBL729118 | 0.81 | CES2 (0.54) | SMN1; SMN2L3MBTL1RAB9ATDP1KDM4E | |
| Benzoylphenylurea SCHEMBL83109 | 0.81 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C | |
| SCHEMBL27258081 | 0.81 | RAB9A (0.47) | SMN1; SMN2L3MBTL1RAB9ATDP1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | SMN1; SMN2 4524/4885L3MBTL1 3838/4885RAB9A 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.