SCHEMBL276852

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16196082	0.94	LMNA (0.45)	LMNAADH1CADH1AADH4ADH1B
	SCHEMBL2498047	0.83	ALDH1A1 (0.50)	LMNATSHRSMN1; SMN2ALDH1A1CYP3A4
	SCHEMBL2180959	0.82	LMNA (0.38)	LMNAADH1CADH1AADH4ADH1B
	SCHEMBL15056445	0.76	LMNA (0.46)	LMNATSHRALDH1A1CYP3A4PLA2G1B
	SCHEMBL7744670	0.76	TSHR (0.42)	LMNAADH1CADH1AADH4ADH1B
	SCHEMBL728434	0.74	ALDH1A1 (0.45)	LMNATSHRSMN1; SMN2ALDH1A1CYP3A4
	SCHEMBL15020380	0.74	LMNA (0.44)	LMNAALDH1A1PLA2G1BPLA2G2AFDPS
	SCHEMBL5192381	0.72	LMNA (0.48)	LMNATSHRPLA2G1BPLA2G2AFDPS
	SCHEMBL15534881	0.72	PLA2G1B (0.55)	LMNATSHRALDH1A1CYP3A4PLA2G1B
	SCHEMBL5191860	0.72	LMNA (0.48)	LMNATSHRPLA2G1BPLA2G2AFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.