Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004391 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL13502531 | 0.79 | KMT2A (0.62) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL3587923 | 0.75 | KMT2A (0.54) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL5777640 | 0.74 | CASR (0.82) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL18176619 | 0.74 | LMNA (0.57) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL15689553 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL3580872 | 0.73 | ALDH1A1 (0.54) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL17643209 | 0.73 | MEN1 (0.80) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL28009020 | 0.72 | CASR (0.60) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL13502461 | 0.72 | CYP1A2 (0.54) | ALDH1A1POLBKMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1960977-A | Quinazoline derivative | BANYU PHARMA CO LTD (JP) | 2007-05-09 | — | — | CN | disclosed |