Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13502531 | 0.77 | KMT2A (0.62) | CASRSMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL5777984 | 0.75 | CASR (1.00) | CASRSMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL3587923 | 0.74 | KMT2A (0.54) | SMN1; SMN2ALDH1A1RAB9ALMNARECQL | |
| SCHEMBL8219402 | 0.74 | L3MBTL1 (0.66) | CASRSMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL13502461 | 0.74 | CYP1A2 (0.54) | CASRSMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL27685271 | 0.72 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL3580872 | 0.72 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1RAB9ALMNARECQL | |
| SCHEMBL28008951 | 0.72 | ALDH1A1 (1.00) | CASRSMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL13101672 | 0.70 | ALDH1A1 (0.79) | ALDH1A1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL5777640 | 0.70 | CASR (0.82) | CASRSMN1; SMN2ALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496915-A | Synthetic method of quinazolinone aromatic compound | UNIV HUAQIAO | 2015-04-08 | — | — | CN | disclosed |