Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909896 | 0.86 | ABL1 (0.47) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL20136961 | 0.83 | TP53 (0.61) | TP53TDP1ESR1ESR2HSD17B1 | |
| SCHEMBL12012444 | 0.79 | HSD17B1 (0.60) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL27704409 | 0.79 | ESR2 (0.47) | TP53TDP1ESR1ESR2HSD17B1 | |
| SCHEMBL27685537 | 0.79 | TDP1 (0.45) | TP53TDP1ESR1ESR2ESRRA | |
| SCHEMBL27704422 | 0.79 | RPS6KA3 (0.45) | TP53TDP1ESRRAHPGDS1PR4 | |
| SCHEMBL12012440 | 0.79 | HSD17B1 (0.51) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL130630 | 0.78 | — | — | |
| SCHEMBL13704109 | 0.78 | ESR1 (0.50) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL6889137 | 0.77 | ESR1 (0.48) | ESR1ESR2HSD17B1HSD17B2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001887-B | Multi-branched polymer and method for producing same | NIPPON SODA CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| CN-101593852-B | Multibranched polymers and process for production thereof | NIPPON SODA CO | 2011-03-02 | — | — | CN | disclosed |
| CN-101593852-A | Multibranched polymers and manufacture method thereof | NIPPON SODA CO (JP) | 2009-12-02 | — | — | CN | disclosed |
| CN-101001887-A | Multi-branched polymer and method for producing same | NIPPON SODA CO (JP) | 2007-07-18 | — | — | CN | disclosed |