Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.48 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15135034 | 0.82 | PRKAB2 (0.49) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL30635318 | 0.79 | ESR1 (0.68) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL857363 | 0.79 | ESR1 (0.68) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL15100009 | 0.79 | HSD17B1 (0.58) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL14270103 | 0.79 | ESR2 (0.51) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL17224046 | 0.79 | ESR1 (0.45) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL6895117 | 0.78 | RPS6KA3 (0.45) | ESR1ESR2HSD17B1HSD17B2ERN1 | |
| SCHEMBL27909896 | 0.77 | ABL1 (0.47) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL27685484 | 0.77 | TP53 (0.45) | ESR1ESR2HSD17B1HSD17B2MGLL | |
| SCHEMBL12012444 | 0.77 | HSD17B1 (0.60) | ESR1ESR2HSD17B1HSD17B2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040191602-A1 | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS, INC. (JP) | 2004-09-30 | — | — | US | disclosed |