SCHEMBL130630

SCHEMBL130630

Cc1ccc(O)c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28119501 0.97 TRPA1 (0.56)
P-Cresol SCHEMBL10553471 0.91 ACHE (0.56)
SCHEMBL26984963 0.83
SCHEMBL23258493 0.81 TRPA1 (0.50)
SCHEMBL12012444 0.81 HSD17B1 (0.60)
SCHEMBL21021957 0.80 TRPA1 (0.48)
SCHEMBL30413683 0.79
SCHEMBL12127 0.79
SCHEMBL27685484 0.78 TP53 (0.45)
P-Cresol SCHEMBL28161633 0.78 ACHE (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6340 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-111218432-B Tyrosinase precursor, encoding gene, preparation and application thereof 中国科学院大连化学物理研究所 2023-03-31 CN claimed
CN-111362841-B Method for para-amination dearomatization of phenol compound 武汉英纳氏药业有限公司 2022-05-03 CN claimed
CN-111362841-A Method for para-amination dearomatization of phenol compound 湖北工业大学 2020-07-03 CN claimed
EP-3142995-B1 PROCESS FOR PREPARING AN UNSATURATED CARBOXYLIC ACID SALT USING AN ARYLOXIDE BASF SE (DE) 2018-03-21 EP claimed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD TOPAZ THERAPEUTICS INC (US) 2026-01-22 US disclosed
US-20260001845-A1 MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS NESTED THERAPEUTICS INC (US) 2026-01-01 US disclosed
EP-4665339-A1 INHIBITING ALPHA V BETA 8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
EP-4098650-B1 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2025-12-10 EP disclosed
US-20250345341-A1 4-Pyrazin-2-ylmethyl-morpholine derivatives and the use thereof as medicament BOEHRINGER INGELHEIM INT (DE) 2025-11-13 US disclosed
WO-2003010120-A1 INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY MERCK PATENT GMBH (DE) 2003-02-06 WO disclosed
CN-1364176-A Processes for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO (JP) 2002-08-14 CN disclosed
CN-1237963-A Quinoline derivatives inhibiting the action of growth factors such as VEGF ZENECA LTD (GB) 1999-12-08 CN disclosed
EP-0832078-B1 N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS PFIZER (US) 1999-10-20 EP disclosed
US-5814648-A N-hydroxyureas as antiinflammatory agents PFIZER INC. (US) 1998-09-29 US disclosed
EP-0590451-A1 Process for acylation of aromatic compounds BASF Aktiengesellschaft (DE) 1994-04-06 EP disclosed
US-4697011-A N-fluoro-N-perfluoromethyl sulfonamides RESEARCH CORPORATION (US) 1987-09-29 US disclosed
US-4524032-A USING FLUORINE GAS IN AN INERT SOLVENT AND COOLING DAIKIN KOGYO CO., LTD. (JP) 1985-06-18 US disclosed