⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12045839 | 0.83 | — | — | |
| SCHEMBL12045842 | 0.81 | — | — | |
| SCHEMBL3318666 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL24401262 | 0.76 | — | — | |
| SCHEMBL1275579 | 0.74 | — | — | |
| Apaflurane SCHEMBL19860 | 0.74 | ALDH1A1 (0.33) | — | |
| Apaflurane SCHEMBL17867718 | 0.70 | ALDH1A1 (0.31) | — | |
| Apaflurane SCHEMBL7649343 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL20189852 | 0.69 | — | — | |
| SCHEMBL21918107 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662107-B2 | Use of 1,1,1,2-Tetrafluoroethane for measuring lung function, especially for determining the functional residual capacity (FRC) of the lungs | Dräger Medical AG & Co. KG (DE) | 2010-02-16 | — | — | US | claimed |
| US-20070196293-A1 | Compositions and methods for treating photo damaged skin | ZARS, INC. | 2007-08-23 | — | — | US | claimed |
| US-20150025051-A1 | FORMULATIONS FOR TREATING SKIN DISORDERS | NUVO RESEARCH INC. (CA) | 2015-01-22 | — | — | US | disclosed |
| US-8741332-B2 | Compositions and methods for dermally treating neuropathic pain | NUVO RESEARCH INC. (CA) | 2014-06-03 | — | — | US | disclosed |
| US-8741333-B2 | Compositions and methods for treating dermatitis or psoriasis | NUVO RESEARCH INC. (CA) | 2014-06-03 | — | — | US | disclosed |
| US-20130022564-A1 | COMPOSITIONS AND METHODS FOR DERMALLY TREATING INFECTIONS | ZARS PHARMA, INC. | 2013-01-24 | — | — | US | disclosed |
| US-20120301517-A1 | TWO OR MORE NON-VOLATILE SOLVENT-CONTAINING COMPOSITIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS | ZARS, INC. | 2012-11-29 | — | — | US | disclosed |
| US-20120294907-A1 | TWO OR MORE SOLIDIFYING AGENT-CONTAINING COMPOSITIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS | ZARS, INC. | 2012-11-22 | — | — | US | disclosed |
| US-20100267678-A1 | FLUX-ENABLING COMPOSITIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS | ZARS PHARMA, INC. | 2010-10-21 | — | — | US | disclosed |
| EP-1968541-A2 | COMPOSITIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS | Zars, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20080019927-A1 | Compositions and methods for dermally treating neuropathy with minoxidil | ZARS PHARMA, INC. | 2008-01-24 | — | — | US | disclosed |
| EP-0536266-A1 | PARTIALLY FLUORINATED ALKANES HAVING A TERTIARY STRUCTURE. | ALLIED SIGNAL INC (US) | 1993-04-14 | — | — | EP | disclosed |
| US-5130345-A | Forming a polyurethane or polyisocyanurate and foaming with a fluorine containing alkanes | ALLIED-SIGNAL INC. (US) | 1992-07-14 | — | — | US | disclosed |
| WO-1992010454-A1 | PARTIALLY FLUORINATED ALKANOLS HAVING A TERTIARY STRUCTURE | ALLIED-SIGNAL INC. (US) | 1992-06-25 | — | — | WO | disclosed |
| US-5118359-A | Method of cleaning using partially fluorinated alkanes having a tertiary structure as solvent | ALLIED-SIGNAL INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-5118360-A | Method of cleaning using partially fluorinated alkenes having a tertiary structure as solvent | ALLIED-SIGNAL INC. | 1992-06-02 | — | — | US | disclosed |
| US-5087777-A | Solvents | ALLIED-SIGNAL INC. (US) | 1992-02-11 | — | — | US | disclosed |
| WO-1992000263-A1 | PARTIALLY FLUORINATED ALKANES HAVING A TERTIARY STRUCTURE | ALLIED-SIGNAL INC. (US) | 1992-01-09 | — | — | WO | disclosed |
| WO-1992000345-A1 | METHOD OF PREPARING FOAM USING A PARTIALLY FLUORINATED ALKANE | ALLIED-SIGNAL INC. (US) | 1992-01-09 | — | — | WO | disclosed |
| US-5059728-A | Solvents; industrial cleaning applications | ALLIED-SIGNAL INC. (US) | 1991-10-22 | — | — | US | disclosed |