Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666835 | 1.00 | KLK5 (0.44) | KLK5CTSSCTSKATMCTSL | |
| SCHEMBL58075 | 0.86 | CTSS (0.47) | KLK5CTSSCTSKATMCTSL | |
| SCHEMBL89265 | 0.86 | CTSS (0.47) | KLK5CTSSCTSKATMCTSL | |
| SCHEMBL9334048 | 0.80 | KLK5 (0.42) | KLK5CTSSCTSKATMCTSL | |
| SCHEMBL22345951 | 0.78 | CTSS (0.48) | KLK5CTSSCTSKATMCTSL | |
| SCHEMBL6671005 | 0.77 | CTSS (0.47) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL13342905 | 0.77 | PPARA (0.46) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL5024738 | 0.77 | CTSS (0.49) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL58394 | 0.77 | CTSS (0.49) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL57550 | 0.77 | CTSS (0.49) | CTSSCTSKATMCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1984881-A | Method for producing enantiomeric form of 2, 3-diaminopropionic acid derivatives | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-06-20 | — | — | CN | disclosed |