Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651833 | 0.81 | MAPT (0.53) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL29533596 | 0.77 | KDM4E (0.68) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL2330779 | 0.77 | KDM4E (0.68) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL10165568 | 0.75 | CDK4 (0.61) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL16450984 | 0.74 | STING1 (0.67) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL7737505 | 0.73 | DYRK1A (0.60) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL19885324 | 0.72 | DYRK1A (0.61) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL18487741 | 0.72 | DYRK1A (0.55) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL690340 | 0.72 | DYRK1A (0.58) | DYRK1AKDM4EALDH1A1ACHEHPGD | |
| SCHEMBL17950654 | 0.72 | DYRK1A (0.55) | DYRK1AKDM4EALDH1A1ACHEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372261-B | Method for preparing 1-bromo/chloro carbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-113372261-A | Method for preparing 1-bromine/chlorocarbazole and derivatives thereof | 中国科学院兰州化学物理研究所 | 2021-09-10 | — | — | CN | disclosed |
| CN-101072754-B | 9,9 ' -and 2,2 ' -substituted 3,3 ' -bicarbazole derivatives for use in semiconductor materials as host matrices for phosphorescent emitters | KONINKL PHILIPS ELECTRONICS NV | 2012-09-05 | — | — | CN | disclosed |
| CN-101346408-A | Polymeric carbazole compounds | KONINKL PHILIPS ELECTRONICS NV (NL) | 2009-01-14 | — | — | CN | disclosed |
| CN-101072754-A | 9,9' -and 2,2' -substituted 3,3' -bicarbazole derivatives for use in semiconductor materials as host matrices for phosphorescent emitters | KONINKL PHILIPS ELECTRONICS NV (NL) | 2007-11-14 | — | — | CN | disclosed |