Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.77 |
| ▸ | TGM2 | P21980 | 1/20 | 0.74 |
| ▸ | KRAS | P01116 | 8/20 | 0.67 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.66 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.66 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.66 |
| ▸ | HINT1 | P49773 | 1/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.63 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.63 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222628 | 0.97 | NT5E (0.74) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL574773 | 0.97 | NT5E (0.74) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL4366555 | 0.97 | NT5E (0.73) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL28597191 | 0.97 | NT5E (0.73) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL28275952 | 0.96 | NT5E (0.75) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL4410906 | 0.96 | NT5E (0.74) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL27819299 | 0.96 | NT5E (0.74) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL401416 | 0.95 | NT5E (0.73) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL8501729 | 0.94 | NT5E (0.74) | NT5ETGM2KRASIMPDH2IMPDH1 | |
| SCHEMBL14125534 | 0.93 | NT5E (0.71) | NT5ETGM2KRASIMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520409-A | Compounds and compositions for intracellular delivery of therapeutic agents | MODERNATX INC | 2019-11-29 | — | — | CN | disclosed |
| CN-105899188-B | Skin emulsion compositions | 大塚制药株式会社 | 2019-11-26 | — | — | CN | disclosed |
| CN-109406467-A | Division aptamer sensor and its application for ATP detection | 商丘师范学院 | 2019-03-01 | — | — | CN | disclosed |
| CN-102641239-B | The pharmaceutical solutions of sirolimus and its derivative for treating CAD | 卡迪纳尔健康515瑞士有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-103958696-B | multiplex nucleic acid analysis | 天昊生物医药科技（苏州）有限公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-104694628-B | Using the activated polymerization nucleic acid reacted by polyphosphoric acid decomposition (APP) | 生命技术公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-105899188-A | Emulsion composition for skin | 大塚制药株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-105705511-A | Deuterated nucleoside prodrugs for the treatment of HCV | 艾其林医药公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-104761604-A | Uridine monophosphate analogue, and preparation method and applications thereof | JIANGSU HANSOH PHARMACEUTICAL | 2015-07-08 | — | — | CN | disclosed |
| CN-104769112-A | Methods and products for expressing proteins in cells | FACTOR BIOSCIENCE INC | 2015-07-08 | — | — | CN | disclosed |
| CN-1973048-B | Terminal-phosphate-labeled nucleotides and methods of use | GE HEALTHCARE BIO SCIENCES | 2015-06-03 | — | — | CN | disclosed |
| CN-104402955-A | Nucleoside phosphoramidate prodrugs | PHARMASSET INC | 2015-03-11 | — | — | CN | disclosed |
| CN-101384729-B | Solid phase sequencing | AMERSHAM BIOSCIENCES CORP | 2014-09-10 | — | — | CN | disclosed |
| CN-101014705-B | Improved enzymes | DSM IP ASSETS BV | 2014-07-30 | — | — | CN | disclosed |
| CN-102177172-A | Compounds and pharmaceutical compositions for the treatment of viral infections | IDENIX PHARMACEUTICALS INC (US) | 2011-09-07 | — | — | CN | disclosed |
| CN-101918425-A | Nucleoside phosphoramidate prodrugs | PHARMASSET INC | 2010-12-15 | — | — | CN | disclosed |
| CN-101384729-A | Solid phase sequencing | AMERSHAM BIOSCIENCES CORP (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-101282968-A | Novel polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide | BAYER HEALTHCARE AG (DE) | 2008-10-08 | — | — | CN | disclosed |
| CN-101014705-A | Improved enzymes | DSM IP ASSETS BV (NL) | 2007-08-08 | — | — | CN | disclosed |
| CN-1973048-A | Terminal-phosphate-labeled nucleotides and methods of use | AMERSHAM BIOSCIENCES CORP (US) | 2007-05-30 | — | — | CN | disclosed |