Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.73 |
| ▸ | TGM2 | P21980 | 1/20 | 0.70 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.65 |
| ▸ | KRAS | P01116 | 8/20 | 0.64 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.63 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.62 |
| ▸ | HINT1 | P49773 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.60 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688115 | 0.95 | NT5E (0.77) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL4410906 | 0.92 | NT5E (0.74) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL574773 | 0.92 | NT5E (0.74) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL28222628 | 0.92 | NT5E (0.74) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL4366555 | 0.92 | NT5E (0.73) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL28597191 | 0.92 | NT5E (0.73) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL28275952 | 0.91 | NT5E (0.75) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL8501729 | 0.91 | NT5E (0.74) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL27819299 | 0.91 | NT5E (0.74) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL14125534 | 0.90 | NT5E (0.71) | NT5ETGM2IMPDH2KRASFUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207891-B1 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | ARCHEMIX LLC (US) | 2012-07-25 | — | — | EP | disclosed |
| US-8101385-B2 | Materials and methods for the generation of transcripts comprising modified nucleotides | ARCHEMIX CORP. (US) | 2012-01-24 | — | — | US | disclosed |
| EP-2207891-A2 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | Archemix Corp. (US) | 2010-07-21 | — | — | EP | disclosed |
| US-20100120024-A1 | Materials and methods for the generation of transcripts comprising modified nucleotides | ARCHEMIX CORP. | 2010-05-13 | — | — | US | disclosed |
| WO-2008078180-A2 | MATERIALS AND METHODS FOR THE GENERATION OF TRANSCRIPTS COMPRISING MODIFIED NUCLEOTIDES | ARCHEMIX CORP. (US) | 2008-07-03 | — | — | WO | disclosed |