Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | FPR3 | P25089 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22892754 | 0.85 | LTA4H (0.45) | PARP1LTA4HFPR3FPR2WNT1 | |
| SCHEMBL25567991 | 0.84 | CHRM1 (0.46) | PARP1FPR3FPR2ARG1ARG2 | |
| SCHEMBL22892866 | 0.83 | CCR5 (0.52) | PARP1FPR3FPR2ARG1ARG2 | |
| SCHEMBL22892876 | 0.83 | CCR5 (0.52) | PARP1FPR3FPR2CARM1PRMT6 | |
| SCHEMBL2858477 | 0.82 | LTA4H (0.44) | PARP1LTA4HSMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL25568006 | 0.81 | EPHX1 (0.45) | PARP1FPR3FPR2SMN1; SMN2EPHX1 | |
| SCHEMBL25579697 | 0.81 | PARP1 (0.45) | PARP1FPR3FPR2ARG1ARG2 | |
| SCHEMBL25579558 | 0.80 | EPHX1 (0.45) | PARP1FPR3FPR2EPHX1EPHX2 | |
| SCHEMBL25568030 | 0.80 | HSD11B1 (0.47) | PARP1FPR3FPR2WNT1DYRK1A | |
| SCHEMBL27570291 | 0.80 | LTA4H (0.48) | LTA4HCARM1PRMT6SMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1980929-A | 4-substituted piperidine derivatives | BIOAXONE THERAPEUTIQUE INC (CA) | 2007-06-13 | — | — | CN | disclosed |