Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688958 | 0.88 | TDP1 (0.62) | TDP1MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28770107 | 0.86 | L3MBTL1 (0.60) | TDP1MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9574413 | 0.78 | CETP (0.69) | MAPTL3MBTL1ALDH1A1HPGDCETP | |
| SCHEMBL27689090 | 0.77 | SLC6A2 (0.48) | TDP1MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9574421 | 0.75 | CETP (0.51) | MAPTL3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL9131197 | 0.74 | PDK1 (0.53) | MAPTL3MBTL1ALDH1A1LMNANPSR1 | |
| SCHEMBL6934961 | 0.74 | RAB9A (0.54) | MAPTL3MBTL1ALDH1A1GLAKMT2A | |
| SCHEMBL27708750 | 0.73 | PDK1 (0.53) | MAPTL3MBTL1ALDH1A1LMNAGLA | |
| SCHEMBL6937514 | 0.73 | MEN1 (0.65) | TDP1MAPTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL6940824 | 0.73 | L3MBTL1 (0.52) | TDP1MAPTL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101070297-B | 2,2,2-trifluoro-N-(2-arylsulf)-a rylamide derivatives and preparing method | UNIV SHANGHAI | 2010-05-19 | — | — | CN | disclosed |
| CN-101070297-A | 2,2,2-trifluoro-N-(2-arylsulf)-a rylamide derivatives and preparing method | UNIV SHANGHAI (CN) | 2007-11-14 | — | — | CN | disclosed |