SCHEMBL2768951

SCHEMBL2768951

CCCC(C)(C)OOC=CC(=O)OCCOC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.41
ATM Q13315 1/20 0.40
APP P05067 3/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALOX5 P09917 1/20 0.31
AKR1B10 O60218 1/20 0.31
AKR1B1 P15121 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2774385 0.88 HCAR2 (0.40) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7691180 0.86 HCAR2 (0.33) HCAR2ATM
SCHEMBL7691585 0.83 HCAR2 (0.35) HCAR2ATM
SCHEMBL464854 0.82 HCAR2 (0.39) HCAR2ATMAKR1B10AKR1B1TSHR
SCHEMBL7685253 0.81
SCHEMBL8762545 0.79
SCHEMBL3758849 0.78 LMNA (0.32) LMNAHSD17B10
SCHEMBL30457671 0.77 LMNA (0.35) LMNAHSD17B10
SCHEMBL3764699 0.77
SCHEMBL9339790 0.75 THRB (0.36) HCAR2ATMTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5140083-A Copolymerized with an unsaturated peroxycarbonate or peroxyester; molding materials; materials handling; heat resistance, impact strength; storage stability NIPPON OIL AND FATS CO., LTD. (JP) 1992-08-18 US claimed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-7842754-B2 Thermoplastic elastomer composition NOF CORPORATION 2010-11-30 US disclosed
EP-0650987-B1 Adhesive fluorine-containing polymer and laminate employing it ASAHI GLASS CO LTD (JP) 2010-04-28 EP disclosed
WO-2009100986-A1 BIOCIDAL COMPOSITIONS FOR PLASTICS BASF SE (DE) 2009-08-20 WO disclosed
EP-1914272-B1 THERMOPLASTIC ELASTOMER COMPOSITION NOF CORP (JP) 2009-05-27 EP disclosed
US-20080221270-A1 Thermoplastic Elastomer Composition NOF CORPORATION (JP) 2008-09-11 US disclosed
EP-1914272-A1 THERMOPLASTIC ELASTOMER COMPOSITION NOF CORPORATION (JP) 2008-04-23 EP disclosed
US-6476125-B1 Fluorine-containing polymer alloy, and method for its preparation and method for its molding ASAHI GLASS COMPANY LTD. (JP) 2002-11-05 US disclosed
US-6335401-B1 ADHESION PRIMER ATOFINA (FR) 2002-01-01 US disclosed
EP-0361400-A2 Thermoplastic resin composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-04-04 EP disclosed
US-4879347-A ETHYLENE POLYMER, VINYL MONOMER, RADICAL POLYMERIZABLE ORGANIC PEROXIDE, FREE RADICAL CATALYST, COPOLYMERIZATION NIPPON OIL AND FATS CO., LTD. (JP) 1989-11-07 US disclosed
US-4877841-A GRAFT POLYMER OF POLYETHYLENE, UNSATURATED MONOMER AND AN UNSATURATED PEROXYCARBONATE; SOLUBILIZERS FOR POLYMER BLENDS NIPPON OIL AND FATS CO., LTD. (JP) 1989-10-31 US disclosed
EP-0338544-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-10-25 EP disclosed
EP-0334296-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-09-27 EP disclosed
US-4839432-A USING A UNSATURATED PEROXY FREE RADICAL CATALYSTS NIPPON OIL AND FATS CO., LTD. (JP) 1989-06-13 US disclosed
EP-0314188-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0307802-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-22 EP disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
EP-0277608-A2 Graft polymerization preformer and method of manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-10 EP disclosed