SCHEMBL464854

SCHEMBL464854

CC(C)(C)OOC=CC(=O)OCCOC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.39
ATM Q13315 1/20 0.37
AKR1B10 O60218 1/20 0.32
AKR1B1 P15121 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TP53 P04637 2/20 0.31
TSHR P16473 2/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2774385 0.85 HCAR2 (0.40) HCAR2ATMTHRB
SCHEMBL7691585 0.83 HCAR2 (0.35) HCAR2ATM
SCHEMBL8526435 0.82 ATM (0.33) HCAR2ATM
SCHEMBL2768951 0.82 HCAR2 (0.41) HCAR2ATMAKR1B10AKR1B1TSHR
SCHEMBL9250932 0.80 HCAR2 (0.31) HCAR2ATM
SCHEMBL10498335 0.79 HCAR2 (0.33) HCAR2ATMALDH1A1
SCHEMBL9339790 0.79 THRB (0.36) HCAR2ATMALDH1A1TP53TSHR
SCHEMBL2772376 0.79 MAPK1 (0.43) HCAR2AKR1B10AKR1B1ALDH1A1TP53
SCHEMBL7688641 0.76
SCHEMBL7685958 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5140083-A Copolymerized with an unsaturated peroxycarbonate or peroxyester; molding materials; materials handling; heat resistance, impact strength; storage stability NIPPON OIL AND FATS CO., LTD. (JP) 1992-08-18 US claimed
CN-107531978-B Methacrylic resin composition 株式会社可乐丽 2020-11-03 CN disclosed
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
EP-1489138-B1 OLEFINIC THERMOPLASTIC ELASTOMER AND MOLDINGS THEREOF NOF CORP (JP) 2012-01-18 EP disclosed
EP-1611946-B1 Microcapsule emulsion and method for producing the same NISSIN CHEMICAL IND (JP) 2011-07-27 EP disclosed
US-7842754-B2 Thermoplastic elastomer composition NOF CORPORATION 2010-11-30 US disclosed
US-7723434-B2 Olefinic thermoplastic elastomer and moldings thereof NOF CORPORATION (JP) 2010-05-25 US disclosed
WO-2009100986-A1 BIOCIDAL COMPOSITIONS FOR PLASTICS BASF SE (DE) 2009-08-20 WO disclosed
EP-1914272-B1 THERMOPLASTIC ELASTOMER COMPOSITION NOF CORP (JP) 2009-05-27 EP disclosed
US-20090005507-A1 GAP-FILLING MEMBER FOR VEHICLES, AND PLATE-LIKE BODY FOR VEHICLE WINDOWS PROVIDED WITH GAP-FILLING MEMBER USING THE SAME ASAHI GLASS COMPANY, LIMITED (JP) 2009-01-01 US disclosed
US-4839432-A USING A UNSATURATED PEROXY FREE RADICAL CATALYSTS NIPPON OIL AND FATS CO., LTD. (JP) 1989-06-13 US disclosed
EP-0314188-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0307802-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-22 EP disclosed
EP-0304039-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304041-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0304040-A2 Thermoplastic resin composition. NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-02-22 EP disclosed
EP-0295706-A2 Thermoplastic resin composition and method for preparing the same Nippon Petrochemicals Co., Ltd. (JP) 1988-12-21 EP disclosed
EP-0289933-A2 Graft polymerization precurser and method manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
EP-0277608-A2 Graft polymerization preformer and method of manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-10 EP disclosed