Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL27709652 | 0.89 | HTT (0.58) | HTTTDP1MAPTNPC1RAB9A | |
| SCHEMBL27709775 | 0.88 | HTT (0.63) | HTTTDP1MAPTNPC1RAB9A | |
| SCHEMBL1949534 | 0.77 | HTT (0.70) | HTTTDP1MAPTNPC1RAB9A | |
| SCHEMBL1949533 | 0.77 | HTT (0.70) | HTTTDP1MAPTNPC1RAB9A | |
| Guanidine SCHEMBL27709634 | 0.76 | HTT (0.68) | HTTTDP1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5427447 | 0.76 | HTT (0.68) | HTTTDP1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5427446 | 0.76 | HTT (0.68) | HTTTDP1MAPTNPC1RAB9A | |
| SCHEMBL7666658 | 0.75 | MAPT (0.66) | HTTTDP1MAPTNPC1RAB9A | |
| SCHEMBL143083 | 0.75 | MAPT (0.66) | HTTTDP1MAPTNPC1RAB9A | |
| SCHEMBL27709604 | 0.75 | HTT (0.59) | HTTTDP1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101111475-A | Antiviral compounds and methods | BIOTRON LTD (AU) | 2008-01-23 | — | — | CN | disclosed |