Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 7/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27710472 | 0.83 | RAB9A (0.46) | DHODHKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL27690492 | 0.82 | EIF4E (0.46) | EIF4EP2RX7KDM4AKDM4BKDM5C | |
| SCHEMBL27690479 | 0.81 | RAB9A (0.45) | DHODHKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL27710483 | 0.78 | RAB9A (0.46) | DHODHKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL27690489 | 0.78 | ECE1 (0.49) | EIF4ERAB9AKDM4EPOLBGAA | |
| SCHEMBL27690469 | 0.77 | KDM4E (0.46) | DHODHKDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL27710479 | 0.72 | RAB9A (0.43) | KDM4AKDM4BKDM5CKDM5BRAB9A | |
| SCHEMBL27710474 | 0.71 | LMNA (0.43) | KDM4AKDM4BKDM5CKDM5BRAB9A | |
| SCHEMBL27745889 | 0.69 | HDAC3 (0.42) | EIF4EP2RX7DHODHRAB9ACDC7 | |
| SCHEMBL19259491 | 0.66 | HDAC3 (0.43) | EIF4EP2RX7DHODHCDC7DBF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101104617-B | Dihydropyrimidine compounds and use of the same in preparing medicament for curing and preventing virosis | BEIJING MOLIK SCIENCE & TECHNOLOGY CO LTD | 2010-06-23 | — | — | CN | claimed |
| CN-101104617-A | Dihydropyrimidine compounds and use for the same in preparing medicament for curing and preventing virosis | BEIJING MOLIK SCIENCE & TECHNO (CN) | 2008-01-16 | — | — | CN | claimed |
| CN-101104617-B | Dihydropyrimidine compounds and use of the same in preparing medicament for curing and preventing virosis | BEIJING MOLIK SCIENCE & TECHNOLOGY CO LTD | 2010-06-23 | — | — | CN | disclosed |
| CN-101104617-A | Dihydropyrimidine compounds and use for the same in preparing medicament for curing and preventing virosis | BEIJING MOLIK SCIENCE & TECHNO (CN) | 2008-01-16 | — | — | CN | disclosed |