Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27691526 | 0.82 | PTGS1 (0.53) | SLC22A12NOTUMPTGS1ENPP2 | |
| SCHEMBL5107107 | 0.76 | BCAT2 (0.48) | TSHRMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL27691534 | 0.76 | CLK4 (0.41) | ADRA2CCLK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6166155 | 0.73 | ADRA2C (0.68) | ADRA2CCLK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3422474 | 0.71 | ADRA2C (0.60) | ADRA2CCLK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31272452 | 0.71 | ADRA2C (0.60) | ADRA2CCLK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL996127 | 0.70 | ADRA2C (0.64) | ADRA2CCLK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL688074 | 0.70 | PRKCI (0.53) | ADRA2CCLK4CYP1A2CYP2C19MAPK1 | |
| SCHEMBL2154026 | 0.70 | CLK4 (0.65) | ADRA2CCLK4TSHRXDHSLC22A12 | |
| SCHEMBL27711670 | 0.70 | BACE1 (0.43) | ADRA2CCLK4XDHSLC22A12IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101061105-B | Potentiators of glutamate receptors | LILLY CO ELI | 2012-05-30 | — | — | CN | disclosed |
| CN-101061105-A | Potentiators of glutamate receptors | LILLY CO ELI (US) | 2007-10-24 | — | — | CN | disclosed |