Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674773 | 0.87 | LMNA (0.43) | CYP19A1KDM4ECYP2C19 | |
| SCHEMBL24182136 | 0.74 | KCNH2 (0.56) | CYP19A1CYP2C19PTGDR2 | |
| SCHEMBL27693251 | 0.73 | PSEN1 (0.41) | CYP19A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL10467514 | 0.73 | PSEN1 (0.41) | CYP19A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL10773483 | 0.72 | TRPA1 (0.40) | CYP19A1KDM4ECPT1ACPT2CPT1B | |
| SCHEMBL10468207 | 0.72 | TRPA1 (0.40) | CYP19A1KDM4ECPT1ACPT2CPT1B | |
| SCHEMBL10773430 | 0.72 | CYP19A1 (0.35) | CYP19A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL12485507 | 0.69 | KDM4E (0.54) | KDM4EPTGDR2HAT1EP300CNR1 | |
| SCHEMBL27418241 | 0.69 | CYP19A1 (0.43) | CYP19A1KDM4EPSEN1PSEN2APH1B | |
| SCHEMBL10773477 | 0.68 | CYP19A1 (0.36) | CYP19A1KDM4EPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87103087-A | As diethylenediamine compound of platelet activation factor-antagonist and preparation method thereof | — | 1987-11-04 | — | — | CN | disclosed |