Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712844 | 1.00 | DNM1 (0.40) | DNM1TDP1MEN1KMT2ATP53 | |
| SCHEMBL7193909 | 0.91 | LTA4H (0.38) | TDP1TP53SMN1; SMN2CES2CES1 | |
| SCHEMBL28770774 | 0.89 | CETP (0.41) | TDP1MEN1KMT2AEPHX2PKM | |
| SCHEMBL27755796 | 0.89 | CETP (0.41) | TDP1MEN1KMT2AEPHX2PKM | |
| Hydrochloric Acid SCHEMBL29128044 | 0.89 | LTA4H (0.36) | TDP1TP53MAPK1SMN1; SMN2CES2 | |
| SCHEMBL27712847 | 0.86 | LMNA (0.38) | TDP1MEN1KMT2AEPHX2PKM | |
| SCHEMBL28770772 | 0.86 | CETP (0.39) | TDP1EPHX2PKMCES2CES1 | |
| SCHEMBL27755795 | 0.86 | CETP (0.39) | TDP1EPHX2PKMCES2CES1 | |
| SCHEMBL27693156 | 0.86 | LMNA (0.38) | TDP1MEN1KMT2AEPHX2PKM | |
| SCHEMBL27713000 | 0.86 | LMNA (0.38) | TDP1MEN1KMT2AEPHX2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107346-B | Urea-based lubricating grease composition | SHELL INT RESEARCH | 2010-12-01 | — | — | CN | disclosed |
| CN-101107346-A | Urea-based lubricating grease composition | SHELL INT RESEARCH (NL) | 2008-01-16 | — | — | CN | disclosed |