SCHEMBL276945

SCHEMBL276945

Oc1ncc2[nH]cnc2n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
KDM4E B2RXH2 2/20 0.59
RXFP1 Q9HBX9 1/20 0.50
CDK2 P24941 2/20 0.46
PAK1 Q13153 1/20 0.44
CCNT1 O60563 1/20 0.39
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CDK7 P50613 1/20 0.39
CDK9 P50750 1/20 0.39
CCNH P51946 1/20 0.39
POLA1 P09884 1/20 0.37
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
SCD O00767 2/20 0.32
PDPK1 O15530 1/20 0.31
GDA Q9Y2T3 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29452971 0.77 ALDH1A1 (0.63) ALDH1A1KDM4ERXFP1CDK2PAK1
2-Aminopurine SCHEMBL28075430 0.77 ALDH1A1 (0.96) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL5748057 0.76 ALDH1A1 (0.61) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL375956 0.74 ALDH1A1 (0.59) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL5170029 0.74 ALDH1A1 (0.59) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL7663294 0.74 ALDH1A1 (0.59) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL29464976 0.74 ALDH1A1 (0.59) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL11486223 0.74 ALDH1A1 (0.59) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL357005 0.74 KDM4E (1.00) ALDH1A1KDM4ERXFP1CDK2PAK1
SCHEMBL3896 0.74 ALDH1A1 (0.59) ALDH1A1KDM4ERXFP1CDK2PAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119455413-A Allopurinol desalination and evaporation device and desalination and evaporation method thereof 宜兴市星宇药业有限公司 2025-02-18 CN claimed
CN-119031915-A Methods and compositions for treating skin proliferative disorders and other skin conditions 不对称疗法有限责任公司 2024-11-26 CN claimed
CN-118048204-A Wafer cleaning liquid for cleaning copper surface after chemical mechanical planarization 华中科技大学 2024-05-17 CN claimed
WO-2023202686-A1 COMPOSITION AND METHOD FOR INHIBITING XANTHINE DEHYDROGENASE (XDH) 上海舶望制药有限公司 2023-10-26 WO claimed
CN-115968815-A Induction method for efficiently producing full-male nibea albiflora triploid 浙江省海洋水产研究所 2023-04-18 CN claimed
WO-2013181296-A2 COMPOSITIONS AND METHODS FOR MANAGING WEIGHT UNIGEN, INC. (US) 2013-12-05 WO claimed
WO-2002092072-A2 DRUGS FOR THE TREATMENT OF THE ALZHEIMER DISEASE NICOX S.A. (FR) 2002-11-21 WO claimed
EP-0741741-B1 MODIFIED OLIGONUCLEOTIDES NOVARTIS AG (CH) 2002-08-28 EP claimed
US-6066447-A INCLUDING NUCLEOSIDE DIMERS WITH MODIFIED BACKBONES; FOR VIRICIDES AND ANTISENSE AGENTS NOVARTIS CORPORATION (US) 2000-05-23 US claimed
US-6011112-A SILYLATED ORGANONITROGEN COMPOUNDS WACKER-CHEMIE GMBH (DE) 2000-01-04 US claimed
WO-1995020597-A1 MODIFIED OLIGONUCLEOTIDES CIBA-GEIGY AG (CH) 1995-08-03 WO claimed
EP-0644196-A1 TTTr as a protecting group in nucleotide synthesis CIBA-GEIGY AG (CH) 1995-03-22 EP claimed
EP-0634927-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-01-25 EP claimed
US-5380521-A Method for obtaining deodorant extract from tissue culture of plants in family oleaceae MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1995-01-10 US claimed
US-5321032-A Peptide compounds and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-06-14 US claimed
EP-0577558-A2 Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates CIBA-GEIGY AG (CH) 1994-01-05 EP claimed
WO-1993017671-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA STATENS SERUMINSTITUT (DK) 1993-09-16 WO claimed
EP-0016845-B1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1983-07-13 EP claimed
US-4341868-A PEROXIDATION; COLORIMETRY; QUANTITAVE ANALYSIS; ONE-STEP; ENTEROBACTER KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-07-27 US claimed
EP-0016845-A1 METHOD AND TEST COMPOSITION FOR THE DETERMINATION OF A SUBSTRATE FOR XANTHINE-OXIDASE, INCLUDING A NOVEL XANTHINE-OXIDASE AND METHOD FOR THE PREPARATION THEREOF KYOWA HAKKO KOGYO CO., LTD. (JP) 1980-10-15 EP claimed