Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MARS1 | P56192 | 2/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RPA1 | P27694 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694750 | 0.87 | TDP1 (0.54) | TDP1PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL5483244 | 0.85 | TAAR1 (0.50) | TDP1PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL27885071 | 0.81 | MAPK9 (0.58) | PTGS1PTGS2MEN1KMT2AMALT1 | |
| SCHEMBL9207571 | 0.80 | PTGS2 (0.58) | PTGS1PTGS2MEN1KMT2AMALT1 | |
| SCHEMBL9206453 | 0.79 | PTGS2 (0.67) | PTGS1PTGS2MEN1KMT2AMALT1 | |
| SCHEMBL6350064 | 0.79 | PTGS2 (0.82) | PTGS1PTGS2MAPK9 | |
| SCHEMBL27714729 | 0.78 | KMT2A (0.89) | MEN1KMT2AATMMARS1L3MBTL1 | |
| SCHEMBL27714718 | 0.77 | KMT2A (0.57) | PTGS1PTGS2MEN1KMT2AMALT1 | |
| SCHEMBL27694758 | 0.76 | CACNA1G (0.84) | PTGS2MEN1KMT2AMALT1ATM | |
| SCHEMBL27694888 | 0.75 | KMT2A (0.71) | PTGS2MEN1KMT2AMALT1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101062916-A | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | claimed |
| CN-101062916-B | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | INST PHARM & TOXICOLOGY AMMS | 2012-12-26 | — | — | CN | disclosed |
| CN-101062916-A | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | POISON MED INST PLA MED ACAD (CN) | 2007-10-31 | — | — | CN | disclosed |