Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769055 | 1.00 | RAB9A (0.47) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29226498 | 1.00 | RAB9A (0.47) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11841950 | 0.94 | BCL2L1 (0.48) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL30434274 | 0.83 | CES2 (0.50) | RAB9ANPC1HTTCES2CES1 | |
| SCHEMBL22937461 | 0.83 | RAB9A (0.47) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL284962 | 0.80 | ESR1 (0.52) | CYP2D6CYP2C9HIF1A | |
| SCHEMBL1421745 | 0.80 | APP (0.49) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7866065 | 0.80 | TSHR (0.48) | RAB9AMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5172480 | 0.80 | ESR1 (0.52) | CYP2D6CYP2C9HIF1A | |
| SCHEMBL637766 | 0.80 | ESR1 (0.52) | CYP2D6CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053382-A1 | Production of alpha-hydroxy-carboxylic acids using a coupled enzyme system | EXCELSYN MOLECULAR DEVELOPMENT LIMITED (GB) | 2004-03-18 | — | — | US | claimed |
| EP-1639119-B1 | METHOD FOR THE MICROBIOLOGICAL ISOMERISATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS | BASF SE (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-1639119-A1 | METHOD FOR THE MICROBIOLOGICAL ISOMERISATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004111257-A1 | METHOD FOR THE MICROBIOLOGICAL ISOMERISATION OF ALPHA-HYDROXY CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | WO | disclosed |