Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RBP4 | P02753 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375701 | 0.90 | GAA (0.49) | GAATDP1RBP4HTR2COPRM1 | |
| SCHEMBL24005789 | 0.78 | GAA (0.49) | GAATDP1RBP4HTR2CHCRTR1 | |
| SCHEMBL17987098 | 0.78 | CHRNB2 (0.53) | GAATDP1RBP4HTR2C | |
| SCHEMBL9687389 | 0.76 | OPRM1 (0.42) | OPRM1OPRK1 | |
| SCHEMBL10740465 | 0.76 | OPRM1 (0.42) | GAAOPRM1OPRK1ALDH1A1 | |
| SCHEMBL19423526 | 0.76 | GAA (0.47) | GAATDP1RBP4HTR2CKDM4E | |
| SCHEMBL19423511 | 0.76 | GAA (0.47) | GAATDP1RBP4HTR2CHCRTR1 | |
| SCHEMBL24775359 | 0.76 | GAA (0.47) | GAATDP1RBP4HTR2CHCRTR1 | |
| Hydrochloric Acid SCHEMBL9688043 | 0.75 | OPRM1 (0.41) | GAAOPRM1OPRK1ALDH1A1 | |
| SCHEMBL22462957 | 0.74 | GAA (0.51) | GAATDP1RBP4HTR2CHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87101647-A | 5-replaces octahydro indolizine analgesics compounds and 7-oxo intermediate | — | 1987-09-16 | — | — | CN | disclosed |